MIAMI - University of Miami researchers have identified a gene that appears to double a person's risk of developing late-onset Alzheimer's disease. They called the finding a small step toward understanding and fighting the debilitating disease, which affects 5 million Americans. I hope that in the next five to 10 years we can see major improvements - a combination of therapies and prevention through exercise, both physical and mental, diet and other things," said Margaret Pericak-Vance. She is director of the John P. Hussman Institute for Human Genomics at the University of Miami Medical School and principal investigator in the study.
TORONTO, April 14 /PRNewswire-USNewswire/ -- Researchers have identified a gene that appears to increase a person's risk of developing late-onset Alzheimer's disease, the most common type of Alzheimer's disease. The research is presented as part of the late- breaking science program at the American Academy of Neurology's 62nd Annual Meeting in Toronto, April 10 - 17, 2010. The gene, abbreviated MTHFD1L, is located on chromosome six. Only recently have common variants in genes other than APOE been convincingly shown to be associated with a person's risk of developing late-onset Alzheimer's disease," said senior author Margaret Pericak-Vance, PhD, Director of the University of Miami Miller School of Medicine's John P. Hussman Institute for Human Genomics in Miami, Florida.
...The research was led by Margaret A. Pericak-Vance, Ph.D., associate dean for human ...
A professor and chief of epidemiology and biostatistics for the USF College of Medicine's department of pediatrics, he has been largely responsible for making USF a hub for epidemiological research in rare diseases and juvenile diabetes. His team established an international data coordinating center that is expected to record and track more than 1 million samples over 15 years as part of studies to identify environmental triggers of Type 1 diabetes, a study known as TEDDY (The Environmental Determinants of Diabetes in the Young). [...] the team is also coordinating and analyzingdata from TrialNet, which studies diabetes prevention in high-risk individuals, as well as treatment of newly diagnosed patients.
...Margaret Pericak-Vance. University of Miami. John P. Hussma...
Medicine & Health
.... Margaret A. Pericak-Vance is the James B. Duke Professor of...
Spending time with daughter, Danica, a med student, knitting, needlework, cooking and her dogs Recognition: UM says most top scientists are proud to have their work cited by their peers 3,000 to 4,000 times in their lifetime.
...Margaret "Peggy" Pericak-Vance. John P. Hussman Institute f...
In what could be a repeat of their blockbuster gene discovery of 1993, scientists at Duke University Medical Center have identified a second gene linked to an increased risk of Alzheimer's. The gene not only appears to predict risk but also pegs the approximate age of onset for the degenerative brain disorder that afflicts 5.3 million Americans.
..., but it needs to be replicated," said Margaret Pericak-Vance, a genetics researcher at Miami Univ...
MIAMI (MCT) - After decades of searching, teams of researchers at the University of Miami and elsewhere have found a gene linked to multiple sclerosis that could lead to breakthroughs in understanding and treating the often-devastating disease. The news was released Sunday in related reports in Nature Genetics and the New England Journal of Medicine. The studies examined more than 10,000 DNA samples from MS patients in the United States and Europe to discover the genetic link.
... common disorders in this way," said Margaret Pericak-Vance, an author on both of the MS papers....
...Margaret Pericak-Vance and Dr. Jeffery Vance of Duke Univer...
WASHINGTON - The leading cause of blindness in the elderly, age- related macular degeneration, has been linked to a gene mutation, raising hopes of earlier detection and possible treatment. Fifteen million Americans have the disease, and that number is expected to double as baby boomers age.
... Yale University School of Medicine and Margaret A. Pericak-Vance of Duke University Medical Center...
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