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Late-onset Alzheimer
79 documents for Late-onset Alzheimer
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TORONTO, April 14 /PRNewswire-USNewswire/ -- Researchers have identified a gene that appears to increase a person's risk of developing late-onset Alzheimer's disease, the most common type of Alzheimer's disease. The research is presented as part of the late- breaking science program at the American Academy of Neurology's 62nd Annual Meeting in Toronto, April 10 - 17, 2010. The gene, abbreviated MTHFD1L, is located on chromosome six. Only recently have common variants in genes other than APOE been convincingly shown to be associated with a person's risk of developing late-onset Alzheimer's disease," said senior author Margaret Pericak-Vance, PhD, Director of the University of Miami Miller School of Medicine's John P. Hussman Institute for Human Genomics in Miami, Florida.
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MIAMI - University of Miami researchers have identified a gene that appears to double a person's risk of developing late-onset Alzheimer's disease. They called the finding a small step toward understanding and fighting the debilitating disease, which affects 5 million Americans. I hope that in the next five to 10 years we can see major improvements - a combination of therapies and prevention through exercise, both physical and mental, diet and other things," said Margaret Pericak-Vance. She is director of the John P. Hussman Institute for Human Genomics at the University of Miami Medical School and principal investigator in the study.
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Dozens of genes have been linked with Alzheimer's, notably the APOE4 gene which raises the risk of developing the disease. Now researchers have identified four additional genes that significantly increase the risk of Alzheimer's disease. Some genes, associated with the most common form of Alzheimer's, late onset, appear linked to known genetic risks according me team at Harvard Medical School in Boston. Rudolph Tanzi of Massachusetts General Hospital, who led the study, said ''We are on the casp of a rare 'science moment' that could alter the way that we diagnose, treat and prevent Alzheimer's disease.
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Two of the most worrisome trends in health care - the soaring rates of Type 2 diabetes and dementia - have biological factors in common. And scientists are beginning to think that is more than just a coincidence. In fact, many now believe that proper control of blood sugar could pay dividends in the future by reducing the number of people stricken by Alzheimer's disease, other forms of dementia and even the normal cognitive decline that comes with age.
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...Even today, when Alzheimer's disease--lust one type of dementia--afflicts as ...
