Thiazolidinediones (TZDs) are a class of drugs which improve insulin receptor sensitivity and reverse the insulin resistance typically seen in type 2 diabetes. Since most type 2 diabetics have too few receptors per body surface area, the TZDs are very useful drugs. The fact that patients on the remaining two TZDs (Avandia and Actos) can gain weight on these drugs is not news. To give just one example as it relates to TZDs, it is clear that controlling blood sugar is important in preventing diabetic end organ damage.
Chicago - A drug designed to reduce insulin resistance in type 2 diabetics appears also to have halted the progression of artery disease. The research raises the prospect that the drug and others in its class someday may be used to reduce heart disease risk, not only in people with diabetes, but also in those with a much more common condition known as pre-diabetes.
..., which is sold under the brand name Actos, already is approved for treating insulin resistan... swelling in the feet and ankles and weight gain. Side effects raise concerns. The fact that m...
I heard your radio show on infection control last week while driving to the hospital to visit my wife. Later that day, because of your show, I observed the following: A nurse arrived to hang another bag of antibiotics. She washed her hands, but before she could complete the task, her phone rang. She pulled it out of her pocket and began talking, stepping into the hall to finish her conversation. When she returned to the room, she dropped her phone in her pocket and hung the antibiotics without washing her hands. It happened so quickly, I did not intervene, but it is frightening.
... I have type 2 diabetes and have been taking Actos for the past 10 years. I have seen notices on TV a... side effects include fluid retention, weight gain, heart failure, headache, sinusitis and musc...
... to continue to grow its franchise product, ACTOS(R) (pioglitazone HCl) and develop its existing pip..., can cause fluid retention and weight gain when used alone or in combination with other ...
... submissions for alogliptin and alogliptin/ACTOS . WILMINGTON, N.C. -- PPD, Inc. (Nasdaq: PPDI) tod... type 2 diabetes patients, especially when weight gain or hypoglycaemia is of concern. . Due to Take...
Gualberto Ruano, M.D., Ph.D., an internist and geneticist, is striving to bring personalized medicine to the clinic. He founded Genomas (www.genomas.net) in 2004 to discover biomarkers to identify patients who are susceptible to known side effects of common drugs. "We are a health-caredelivery company developing a biomarker platform to improve the use of drugs already on the market" says Dr. Ruano, president and CEO. The PhyzioType technology, which the FDA classifies as a medical device, is in the research-and-development stage. Genomas plans to submit its biomarker platform for FDA approval by 2009. Each PhyzioType system requires about 20 biomarkers or SNPs to predict the side effects of a drug. Patients are pending on some ensembles of biomarkers and bioinformatic methods or interpr...
... prediabetic metabolic symptoms like weight gain and increases in blood lipid levels. "We can ...The oral thiazolidinedione drugs Actos® and Avandia® are used to lower insulin resistance...
... to continue to grow its franchise product, ACTOS(R) (pioglitazone HCl) and develop its existing pip..., can cause fluid retention and weight gain when used alone or in combination with other ...
... drugs and dangerous in comparison with ACTOS or pioglitazone, they are recruiting from all over... it earlier, but this is when it began to gain force and more people began using this and getting... And that it would carry some weight. We also would like to work with you to get your b...
To: MEDICAL EDITORS Contact: Jocelyn M. Gerst of Takeda Pharmaceuticals North America, Inc., +1-224-554-5542; or Amy Losak of Ketchum, +1-646-935- 3917
... doctor immediately if you experience rapid weight gain, fluid retention, or shortness of breath. Do ...
Composite Endpoint Included Body Weight, Blood Pressure and Lipid Levels . LISBON, Portuga...
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